Since childhood, Sam Grandy and Roy Courtright have been best friends. They grew up in the same prosperous community, went to the same prep school, and later entered the same university. After Sam's father died, Roy's father looked after him. At one point Sam dated Roy's sister, Robin. As best friends, they share a close and loving bond, often stronger than the relationships other men share with their girlfriends, siblings, or wives.

But in the twenty years since their friendship began, their fundamental differences have become more apparent and their relationship has grown strained. More and more often they realize they are opposites -- one a womanizer, the other a devoted husband; one careless with money, the other frugal; one independent, the other needy. Do these differences threaten their friendship -- or are the dissimilarities what make it possible? Can they escape the ties of their past, or are they intrinsically bound until death? When Sam's health begins to falter, he draws Roy into his life again -- and into a chain of deceit, sex, delusion, death, and love such as only a best friend could.

Thomas Berger has enthralled millions of readers for almost fifty years with his psychologically complex, sharp-sighted storytelling. With exquisite wit and insidious wisdom, Best Friends weaves a powerful tale about friendship -- and the complex loyalties involved.