Part One of this entertaining exploration of screwball comedies and their later offspring begins in the mid-1930s discussing the careers of popular stars such as Cary Grant and Carole Lombard and well-known supporting players like Walter Connally and Ralph Bellamy (also Asta the dog, top animal star of the 1930s!). Writers and directors are given their due: Frank Capra, Howard Hawks and Preston Sturges, just to name a few.

Part Two, the meat of the book, takes an in depth look at the films, from the genre's inception (1934's It Happened One Night) to the recent 2003 Down with Love, and the stars that appear in them—Clark Gable, Claudette Colbert, Julia Roberts, Richard Gere—ending with some thoughts about the future.